
产品货号:
Z13612
中文名称:
CD82抗体
英文名称:
Anti-CD82 Antibody
产品规格:
0.1mg
发货周期:
1~3天
产品价格:
询价
抗体名称 | Anti-CD82 Antibody |
指标别名 | 4F9;C33;C33 antigen;CD82 antigen;CD82 molecule;CD82;KAI1;GR15;IA4;Inducible membrane protein R2;KAI1;Metastasis suppressor Kangai 1;R2;SAR2;ST6;Tetraspanin 27;Tspan 27;TSPAN27 |
克隆性 | Polyclonal |
检验物种 | human,mouse,rat |
应用范围 | ELISA,WB,IHC,IF |
基因名称 | CD82 |
抗体来源 | Rabbit |
抗体类型 | IgG |
免疫原 | KAI1 antibody was raised against a 15 amino acid synthetic peptide from near the carboxy terminus of human KAI1.The immunogen is located within the last 50 amino acids of KAI1. |
计算分子量 | 30kDa |
成分 | KAI1 Antibody is supplied in PBS containing 0.02% sodium azide. |
纯化方式 | KAI1 Antibody is affinity chromatography purified via peptide column. |
浓度 | 1mg/mL |
产品形态 | 溶液 |
保存条件 | 4℃可保存3个月,-20℃可保存1年。 |
背景资料 | KAI1 was initially identified from a T-cell activation study as a four-transmembrane protein that plays an accessory role in T-cell activation,and was later determined to act as a cancer metastasis suppressor gene.This protein is ubiquitously expressed at moderate to high levels in most tissues,but its expression is downregulated during tumor progression.The loss of KAI1 and p53 is associated with poor survival for prostate and other cancer patients.Recently,KAI1 was found to interact with DARC,the Duffy antigen for chemokines using a yeast two hybrid screen.It is thought that tumor cells dislodged from the primary tumor and expressing KAI1 interact with DARC proteins expressed on vascular cells,transmitting a senescent signal to the tumor cells,while tumor cells that have lost KAI1 expression can proliferate and potentially give rise to metastases.At least two isoforms of KAI1 are known to exist. |
Uniprot ID | P27701 |
基因名全称 | CD82 molecule |
蛋白名全称 | CD82 molecule |
推荐稀释比 | KAI1 antibody can be used for detection of KAI1 by Western blot at 0.5 ~ 1μg/mL.Antibody can also be used for immunohistochemistry starting at 2.5μg/mL.For immunofluorescence start at 20μg/mL.Antibody validated:Western Blot in human samples;Immunohistochemistry in human samples and Immunofluorescence in human samples.All other applications and species not yet tested. |
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